Wii

這是一位將滿八十六歲的"年輕人"最有精神和活力的時候. Let's do it Wii..........................................................................

Arcos 節慶日

今早近八點時帶Boris出去辦牠的大事, 往 Arcos 教堂方向走不到30公尺就聽到有幾位熟悉村民的交談聲音, 再往前走就看到大家正忙著準備今天"拜拜"的祭壇, 原來今天是我們村節慶日的第一天, 教堂有一個比較特別的Corpus Christi彌撒活動, 大家正忙著裝飾往教堂道路, 大概有一百公尺長的距離, 利用附近山上和庭院種植的花草做材料彩繪到道路上, 趕快的將Boris帶回家, 怕牠會去破壞已做好的花草彩繪, 然後我們帶著剪刀加入大夥的行列, 幫忙處理彩繪所需的花草材料, 同時利用時間拍了一些照片和大家分享我們今年 Arcos da Condesa 節慶活動. 可惜的是今天天氣有點不好, 斷斷續續的飄著毛毛細雨.

最牛的彩券

下個星期是本村 一年一度的節慶周, 為了籌措節慶基金, 主辦單位印製彩券發售, 每張 2.5 歐元, 幾天前 Chelo (去年本村村民聚餐照片中與哈密瓜共舞的那一位女士) 向我兜售, 我[慷慨]解囊買了[兩張] (其實這是額外支出, 本村村民住戶每家都會捐贈不少錢贊助節慶, 我們也不例外), 彩券到手時一瞧才知道抽獎時間竟然是18日凌晨一點半開獎 (17日晚上十點開始有現場歌舞團駐唱表演, 開獎活動就在表演中進行), 彩券持有人必須在場參加開獎, 若不在現場就算是放棄資格, 中獎者只有一名, 獎品是 - 如彩券上印上的動物 - 小牛一隻, 這是我今生所買過最[牛]的彩券, 祝我們中獎吧! 若真中了獎還真不知道小牛要養在哪裡, 跟Boris不知合不合得來, 還是直接請好友們週末來吃烤牛排好了.

Salamander

沒想到連續兩年冬春交替時期曾來我們家泳池拜訪的嶸螈親族竟然因其再生能力登上了這一期的[自然]雜誌, 令人羨慕. 照片上的這隻今年一月中還在泳池產下不少的小嶸螈, 可惜因為照顧不周而犧牲了, 轉載期刊摘要算是紀念這些犧牲掉的小生命吧.

Nature 460, 60-65 (2 July 2009)

Cells keep a memory of their tissue origin during axolotl limb regeneration

Martin Kragl1,3,5,6, Dunja Knapp1,3,5, Eugen Nacu1,3, Shahryar Khattak1,3, Malcolm Maden4, Hans Henning Epperlein2 & Elly M. Tanaka1,3
Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108,
Institute of Anatomy, Medical Faculty, University of Technology Dresden, Fetscherstrasse 74,
Center for Regenerative Therapies, University of Technology Dresden, Tatzberg 47/49, 01307 Dresden, Germany
The Regeneration Project, McKnight Brian Institute, University of Florida, Rm 326 Bartram Hall, Gainesville, Florida 32611, USA
These authors contributed equally to this work.
Present address: Institute of Metabolic Physiology, Heinrich-Heine-Universität Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany.
Correspondence to: Elly M. Tanaka1,3 Correspondence and requests for materials should be addressed to E.M.T. (Email: elly.tanaka@crt-dresden.de).

Abstract

During limb regeneration adult tissue is converted into a zone of undifferentiated progenitors called the blastema that reforms the diverse tissues of the limb. Previous experiments have led to wide acceptance that limb tissues dedifferentiate to form pluripotent cells. Here we have reexamined this question using an integrated GFP transgene to track the major limb tissues during limb regeneration in the salamander Ambystoma mexicanum (the axolotl). Surprisingly, we find that each tissue produces progenitor cells with restricted potential. Therefore, the blastema is a heterogeneous collection of restricted progenitor cells. On the basis of these findings, we further demonstrate that positional identity is a cell-type-specific property of blastema cells, in which cartilage-derived blastema cells harbour positional identity but Schwann-derived cells do not. Our results show that the complex phenomenon of limb regeneration can be achieved without complete dedifferentiation to a pluripotent state, a conclusion with important implications for regenerative medicine.
(copy from http://www.nature.com/nature/journal/v460/n7251/abs/nature08152.html)